Ventilated Awake
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The role of pleural pressure and airway closure during mechanical ventilation

door Jan van Egmond | feb 7, 2025 | Publications

In their recent article, Piquilloud et al.1 explain the value of knowing pleural pressure (Ppl) for the individual calculation of compliance/elastance of thorax wall and lungs. In the interpretation of Ppl values some important issues must be included: Ppl in the...

Negative pressure ventilation, an umbrella against ventilator induced lung injury

door Jan van Egmond | feb 7, 2025 | Publications

In their clear overview on ventilator-induced lung injury (VILI) in Intensive Care Medicine, Gattinoni and colleagues1 call to mind that mechanical ventilation (MV) should provide sufficient gas exchange without generating additional injury. However, current MV does...

Airway closure during mechanical ventilation of acute respiratory distress syndrome patients

door Jan van Egmond | feb 7, 2025 | Publications

With interest we read the article “Phenotypes of esophageal pressure response to the change of positive end-expiratory pressure in patients with moderate acute respiratory distress syndrome” by Cheng et al.1. The peripheral airway closure might be the underlying...

Negative pressure ventilation protects the brain

door Jan van Egmond | feb 7, 2025 | Introductory articles, Publications

Dear Editor, With great interest we have read the recent paper in the journal ‘Critical Care,’ titled: ‘The future of intensive care: delirium should no longer be an issue,’ by Kotfis et al. 1. Kotfis et al. state that the major factor to prevent delirium...

Recent Posts

  • The role of pleural pressure and airway closure during mechanical ventilation
  • Negative pressure ventilation, an umbrella against ventilator induced lung injury
  • Airway closure during mechanical ventilation of acute respiratory distress syndrome patients
  • Negative pressure ventilation protects the brain
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